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Solvent-free Medical Adhesives

Modern medical device manufacturers are considering adhesive solutions designed to eliminate or reduce solvents while delivering the performance standards healthcare applications require. 


Performance Without Compromise

Advanced solvent-free adhesive technologies address growing market demand for safer, more sustainable medical films, tapes, and drapes while meeting stringent regulatory requirements and supporting improved patient outcomes. 


Opportunities for Medical Innovation

Organizations have significant opportunities to enhance patient care, improve manufacturing efficiency, and strengthen competitive positioning through advanced adhesive technology. Our advanced medical adhesive portfolio, featuring solvent-free formulations, delivers patient comfort and clinical outcomes while meeting evolving industry standards and regulatory requirements.

Patient Experience and Clinical Outcomes

Clinical wear trials demonstrate that advanced adhesive formulations like Avery Dennison’s Solvent-Free adhesives can significantly reduce pain scores during removal and minimize skin irritation. Improved patient comfort enhances product compliance, supports better clinical outcomes, and strengthens product reputation among healthcare providers. These patient experience advantages create opportunities for differentiation in competitive markets.

Regulatory Advantage and Market Access

Proactive adoption of advanced adhesive formulations positions medical companies ahead of evolving regulatory requirements. California's Proposition 65, ICH Q3C guidelines restricting solvents to 890 parts per million maximum, REACH regulations, and the European Green Deal establish increasing focus on solvent reduction. Early transition to compliant technologies ensures continued market access.

Clinical Performance Benefits


Maintaining Fluid Management Capabilities

Medical applications requiring moisture control benefit from our solvent-free adhesive's robust fluid handling capacity. The technology maintains the absorbent properties essential for various medical applications, including wound care, ostomy flanges, advanced wound dressings, and surgical uses, while eliminating solvents. This ensures effective exudate management without compromising patient safety.

Breathability for Patient Comfort

The improved moisture vapor transmission rate in our solvent-free formulation directly addresses patient comfort during extended wear periods. The adhesive allows skin to breathe more effectively while maintaining secure adhesion, reducing the risk of skin maceration. This enhanced moisture management supports natural healing processes in wound care applications while preventing moisture buildup that can compromise adhesive performance or cause patient discomfort.

Validated Adhesion Performance

Comprehensive testing confirms that our solvent-free adhesive technology delivers comparable performance to established solvent-based systems in critical adhesion parameters. Standardized tests demonstrate equivalent bonding strength, ensuring dressings, films and drapes maintain secure attachment throughout their intended wear period. This performance validation provides manufacturers with confidence that transitioning to solvent-free technology will not compromise product reliability or clinical outcomes.

Application-Specific Solutions


Incise Film Applications

Surgical incision films using solvent-free technology maintain transparency for surgical site monitoring while delivering secure adhesion. Compatible with both Gamma and EtO sterilization methods, offering manufacturing process flexibility.

Wound Care Dressings

Advanced wound dressings incorporating solvent-free adhesives create optimal healing environments through improved moisture vapor transmission that supports natural healing processes while maintaining protective wound site sealing.

Surgical Applications

Surgical drape tapes and construction materials benefit from strong tie layer anchoring under challenging wet conditions, with enhanced breathability enabling extended application without complications.

Featured products

MED 5570U

MED 5570U

MED 5570U is a single-coated, soft, pliable, transparent polyurethane film with a solventless acrylic adhesive. This product's thin and conformable film offers a high degree of user comfort, while its transparency allows for wound or site visibility; in some applications, it can act as a barrier to assist in decreasing the risk of bacterial infections.

Learn more about MED 5570U here
Key benefits
  • Advanced acrylic adhesive system
  • Compatible with gamma and ethylene oxide sterilization
  • Die-cuttable with optional handling bars
  • Fluid handling capacity with advanced acrylic formulation
  • Improved moisture vapor transmission rate for enhanced breathability
  • Reliable performance validated against solvent-based adhesives in key adhesion tests
  • Optimized coat weight for efficient material usage

Sustainability and Environmental Benefits

Solvent-free technology delivers measurable environmental impact reductions recognized by industry leadership. The Radtech 2024 Sustainability Award acknowledged these achievements:

  • 25% to 35% lower CO2 emissions compared to solvent acrylics

  • Reduced energy consumption through eliminated solvent processing requirements

  • Elimination of water and solvent dependency in manufacturing processes

  • Safer manufacturing environments with zero volatile organic compound emissions

Collaborative Development for Medical Adhesive Success

Successfully implementing solvent-free adhesive technology depends on working with partners who understand your unique adhesive requirements and regulatory challenges. Our 50 years of medical adhesive science experience supports manufacturers through every development phase, from initial concept through commercial launch and scale-up.

Our expanding solvent-free technology platform adapts to your specific application demands, whether you're developing next-generation wearable incise films, advanced wound care systems, or surgical products.

Contact our team to explore solvent-free adhesive solutions that enhance performance while improving patient safety and regulatory compliance.

Get in touch with our specialists

Avery Dennison Medical combines materials science expertise with deep understanding of healthcare applications to develop innovative adhesive solutions. Our solvent-free UV acrylic technology represents the future of medical adhesives, delivering superior performance while prioritizing patient safety and environmental responsibility.

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Adhesive Technologies

Interested in learning more about how we can help drive your next innovation?

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